Product info
How nutraMetrix Isotonix® Multivitamin Fifty Plus Benefits You*
Adequate nutrition during the golden years has its challenges. As we age our bodies become less efficient at absorbing crucial nutrients, so it's important to be sure we’re getting the right vitamins and minerals. A good way to make sure you get all the nutrients you need is by taking a daily multivitamin supplement. Although a healthy diet is crucial to getting the nutrients your body needs, as we mature we often experience smaller appetites, loss of taste, dietary restrictions due to medical problems and stress can still impact our food choices and food quality, which can impede us from achieving our optimal nutrient intake via food alone.
People over 50 should take special care that they are getting enough B12 – found naturally in meats, fish, eggs and dairy products, along with folate – found in animal products and leafy vegetables. These are nutrients that the body absorbs less of as you get older. Getting enough B12 and folate supports the formation of red blood cells and promotes healthy nerve function. Adequate intake of B12 and folate can also support liver, heart and cognitive health.
Vitamin C is an antioxidant, and wards off free radicals. Getting enough vitamin C is especially important as you get older because it supports immune health. Vitamin C supports healthy cholesterol levels in the blood and fights free radicals to support heathy eyes as we mature. Calcium and vitamin D are also critical nutrients to take in as you age, to help maintain bone strength; especially in women. In addition to needing added vitamins, aging adults need added minerals as well. Along with calcium, your aging body needs magnesium, chromium, potassium, zinc and many more to help you maintain good health.
Making sure you get the proper nutrients may not turn back the clock, but it can help keep it wound up. nutraMetrix Isotonix Multivitamin Fifty Plus is an isotonic-capable food supplement that has been specially formulated with a broad spectrum of nutrients that help support the health of adults 50+ and help keep your clock ticking efficiently. nutraMetrix Isotonix Multivitamin Fifty Plus supplements dietary deficiencies and helps maintain normal metabolic functioning, essential to keeping you healthy as you age.
Primary Benefits of nutraMetrix Isotonix® Multivitamin Fifty Plus*
- Helps promote normal levels of vitamins and minerals in aging adults
- Provides nutrients essential for numerous processes in the body
- Contains activated forms of select B-vitamins to help ensure optimal utilization by the body
- B Vitamins are essential for many key functions in the body
- Vitamins B1, B2, B3, and biotin participate in different aspects of energy production
- Vitamin B5 is involved in the Kreb’s cycle of energy production and is needed to make the neurotransmitter acetylcholine. B5 is also essential in producing, transporting, and releasing energy from fats
- Vitamin B6 is essential for amino acid metabolism
- Vitamin B12 and folate facilitate steps required for cell division
- Folate helps form building blocks of DNA, the body’s genetic information, and building blocks of RNA, needed for protein synthesis in all cells.
- Aids in red blood cell formation
- Involved in the metabolism of proteins, fats, and carbohydrates
- Necessary for proper functioning of the nervous system, bone marrow and intestinal tract (B-vitamin deficiencies appear in these tissues first)
- Helps support brain health/cognitive health
- Helps maintain normal production of neurotransmitters
- Promotes/supports a healthy nervous system
- Supports a healthy heart
- Promotes cardiovascular health
- Supports healthy vision and eyes
- Supports healthy immune functions
- Supports skeletal and muscle health
- Supports healthy teeth and gums
- Provides a strong antioxidant defense

Embrace Your Age
Product Classifications
Vegetarian - This product is vegetarian
Isotonic-Capable Drinkable Supplements - Easy-to-swallow supplements in liquid form are immediately available to the body for absorption
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity

Isotonix Delivery System

Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.
Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream.With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
Key Ingredients
Vitamin A is a fat-soluble vitamin. Sources of vitamin A include organ meats (such as liver and kidney), egg yolks, butter, carrot juice, squash, sweet potatoes, spinach, peaches, fortified dairy products and cod liver oil. Vitamin A is also part of a family of compounds including retinol, retinal and beta-carotene. Beta-carotene, also known as pro-vitamin A, can be converted into vitamin A when additional levels are required. All of the body’s tissues need Vitamin A to support normal growth and repair. Vitamin A helps to promote healthy vision, normal bone growth and supports an antioxidant defense and a healthy immune system. Taking beta-carotene by mouth along with vitamin C, vitamin E, and zinc daily, seems to support eye health.*
Vitamin B1 is a water-soluble vitamin that promotes normal processing of carbohydrates, fat and protein. Every cell of the body requires vitamin B1 to form the fuel the body runs on, adenosine triphosphate (ATP). Vitamin B1 promotes normal functioning of nerve cells and supports carbohydrate metabolism. B1 helps maintain a healthy nervous system by supporting the normal production of the neurotransmitters acetylcholine and gamma-aminobutyric acid (GABA).
Vitamin B2 is a water-soluble vitamin that promotes the normal processing of amino acids and fats, activation of vitamin B6 and folate, and supports the conversion of carbohydrates into the fuel the body runs on, adenosine triphosphate (ATP). It also promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth.
Niacin, also known as vitamin B3, supports energy production in the body. It works with vitamin B1 and vitamin B2 to support the release of energy from carbohydrates. Similar to vitamin B6 and folate, niacin helps support the body's normal renewal of tissues.
Pantothenic acid, also called vitamin B5, is a water-soluble vitamin involved in energy production and the formation of the neurotransmitter acetylcholine, which supports brain health. Pantothenic acid works together with vitamin B1, vitamin B2, and vitamin B3 to make the fuel our body runs on, ATP. It also promotes the normal production, transport, and release of energy from fats. Pantothenic acid promotes the normal secretion of hormones.
Vitamin B12 (cobalamin) is naturally found in animal products, especially organ meats such as liver, with small amounts derived from peanuts and fermented soy products, such as miso and tempeh. It is essential that vegetarians consume a vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. It supports the maintenance of cells, especially those of the nervous system, bone marrow and intestinal tract. Vitamin B12 is important in homocysteine metabolism (homocysteine is an amino acid that is formed within the body). Normal homocysteine levels are important for maintaining cardiovascular health. Folate and B12, in their active coenzyme form, help to maintain healthy blood levels of homocysteine.
Folate is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans, peas and Brewer’s yeast are the best sources. Folate boosts the benefits of B12 supplementation. These two B vitamins join forces and work together to help maintain normal red blood cells. Folate assists in the normal utilization of amino acids and proteins, as well as supporting the construction of the material for DNA and RNA synthesis, which is necessary for all bodily functions. Scientific studies have found that when working in tandem with folate, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system.
Biotin, a water-soluble B-vitamin, acts as a coenzyme to support the normal metabolism of protein, fats, and carbohydrates. Biotin can be found in food sources such as egg yolks, peanuts, beef liver, milk, cereals, almonds and Brewer’s yeast. Biotin promotes healthy cell growth, the production of fatty acids, metabolism of fats and amino acids. It supports the citric acid cycle, which is the process in which energy is generated during exercise. Biotin is also helpful in maintaining steady blood sugar levels, and is often recommended to support strong hair and nails.Biotin also supports various metabolic chemical conversions. Aging adults get the energy they need from food through metabolism - the chemical reactions in the body's cells that convert the fuel from food into the energy needed to do everything from moving to thinking.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that has a number of biological functions. Vitamin C is found in peppers (sweet, green, red, hot red and green chili), citrus fruits and brussel sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries. Nuts and grains contain small amounts of vitamin C. It is important to note that cooking destroys vitamin C activity.
Regular sunlight exposure is the main way that most humans get their vitamin D. Food sources of vitamin D are vitamin D-fortified milk (100 IU per cup), cod liver oil, and fatty fish such as salmon. Small amounts are found in egg yolks and liver. Vitamin D promotes the absorption of calcium and phosphorus and supports the production of several proteins involved in calcium absorption and storage. Vitamin D works with calcium to promote hard, strong bones. It works to promote active transport of calcium out of the osteoblasts into the extra-cellular fluid and in the kidneys, promotes calcium and phosphate uptake by renal tubules. Vitamin D also promotes the normal absorption of dietary calcium and phosphate uptake by the intestinal epithelium. It promotes healthy growth and repair of tissues, and supports overall skin health.*
The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amounts of vitamin E (about two thirds of the RDA in ¼ cup) and there are trace amounts in corn oil and soybean oil. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols. Vitamin E is available in a natural or synthetic form. In most cases, the natural and synthetic forms are identical except the natural form of vitamin E is better absorbed and retained in the body. The natural form of alpha-tocopherol is known as "d-alpha tocopherol,” as found in Isotonix Multivitamin for Seniors.) The synthetic "dl-" form is the most common form found in dietary supplements. For those individuals watching their dietary fat consumption, which is relatively common in the world of dieting, vitamin E intake is likely to be low, due to a reduced intake of foods with high fat content.
Calcium is found in milk, cheese, yogurt, corn tortillas, Chinese cabbage (Napa), kale and broccoli. Calcium is an essential mineral with a wide range of biological roles. Calcium exists in bone primarily in the form of hydroxyapatite (Ca10 (PO4)6 (OH) 2). Hydroxyapatite comprises approximately 40 percent of the weight of bone. The skeleton has an obvious structural requisite for calcium. The skeleton also acts as a storehouse for calcium. Apart from being a major constituent of bones and teeth, calcium promotes normal muscle contraction, nerve conduction, cardiovascular health, the production of energy and helps maintain a healthy immune system.
Chromium is found naturally in some cereals, meats, poultry, brewer’s yeast, broccoli, prunes mushrooms, fish and beer. Chromium is an essential trace mineral that helps to maintain normal blood sugar levels and blood levels of cholesterol and other fats. Chromium combines to form something in the body called glucose tolerance factor or GTF, which helps maintain normal blood sugar levels.
Iodine is found in most seafood and in iodized salt. The trace element is also present in more than a hundred enzyme systems such as energy production, nerve function and hair and skin growth. One of iodine's main functions includes supporting the thyroid gland in producing thyroid hormones thyroxin and tri-iodothyronine, which helps regulate and maintain a properly functioning metabolism.
Manganese is a mineral found in large quantities in both plant and animal matter. The most valuable dietary sources of manganese include whole grains, nuts, leafy vegetables and teas. Manganese is concentrated in the bran of grains, which is often removed during processing. There are several forms of supplementary manganese including manganese gluconate, manganese sulfate, manganese ascorbate, and manganese amino acid chelates.
Foods rich in potassium include fresh vegetables and fruits such as bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps to maintain normal fluid balance in the body. It also supports a wide variety of biochemical and physiological processes. Among other things, it supports normal nerve impulses, cardiac, skeletal and smooth muscle contractions, energy production, synthesis of nucleic acids, and helps maintain intracellular tonicity and normal blood pressure. Potassium promotes normal muscle relaxation and insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes proper heartbeat. Potassium is important in releasing energy from protein, fat, and carbohydrates during metabolism.
The best dietary sources of selenium include nuts, unrefined grains, brown rice, wheat germ, and seafood. In the body, selenium functions as part of an antioxidant enzyme called glutathione peroxidase as well as promoting normal growth and proper usage of iodine in thyroid functioning. Selenium also supports the antioxidant effect of vitamin E and is often added to vitamin E supplements. As part of the antioxidant, glutathione peroxidase, selenium plays a direct role in the body’s ability to protect cells from free radicals.
Zinc is largely found in fortified cereals, red meats, eggs, poultry and certain seafood including oysters. It is a component of multiple enzymes and proteins. It also supports the body’s regulation of gene expression. Zinc is an essential trace mineral that has functions in approximately 300 different enzyme reactions. Thus, zinc plays a part in almost all biochemical pathways and physiological processes. More than 90 percent of the body’s zinc is stored in the bones and muscles, but zinc is also found in virtually all body tissues. It has been claimed that zinc supports normal healing, supports the immune system and promotes a healthy prostate gland. Because zinc is involved in such a great number of enzymatic processes it has been found to support a large range of functions including digestion, energy production, growth, cellular repair, collagen synthesis, bone strength, cognitive function and carbohydrate metabolism.
FAQs*
A vitamin may be broadly defined as a substance that is essential for the maintenance of normal metabolic function, but which is not produced in the body and therefore must be consumed from a source outside the body. They are necessary elements in the process of converting food to energy and in the growth and repair of body tissue. Reduction of vitamin levels over extended periods can result in vitamin deficiency. Deficiencies can be easily avoided by adequate vitamin intake to help fill the gaps in one’s diet.*
2. What separates nutraMetrix Isotonix Multivitamin Fifty Plus from other multivitamins?
nutraMetrix Isotonix Multivitamin Fifty Plus is formulated using the Isotonix Delivery System, which allows for nutrients to be delivered efficiently from your stomach to your intestines for maximum concentration. This means less nutritional value is lost, and you are getting a maximum benefit from this multivitamin.
3. What is the difference between nutraMetrix Isotonix Multivitamin and nutraMetrix Isotonix Multivitamin Fifty Plus?
nutraMetrix Isotonix Multivitamin Fifty Plus has been specifically formulated to focus on specific nutrients that we need as we age. As you age, your body’s physiological needs, as well as your dietary intake changes. nutraMetrix Isotonix Multivitamin Fifty Plus takes into consideration these physiological changes, the Recommended Dietary Reference Intakes (DRI) and the average American diet, to bring you a formula designed to help meet the changing health needs of aging adults.
4. Why doesn’t nutraMetrix Isotonix Multivitamin Fifty Plus contain higher amounts of needed nutrients like Vitamin D3 and Calcium?
It is important to recognize that increased amounts of nutrients like Vitamin D3 and Calcium are essential to the health of aging individuals, however their addition to a multivitamin in higher amounts would not be properly rationed to the other ingredients in the multivitamin, essentially rendering the formulation less beneficial overall. nutraMetrix Isotonix Multivitamin Fifty Plus pairs well with nutraMetrix Isotonix Vitamin D with K2 and Isotonix Calcium Complete to get all the nutrients you need in the proper ratio.
5. How can vitamins A, C E and zinc help support my vision health as I age?
Vitamins A, C E and zinc as found in nutraMetrix Isotonix Multivitamin Fifty Plus, are known to play a role in maintaining eye health and structure as you age. They also provide antioxidant protection.*
6. What type of vitamin E is in the nutraMetrix Isotonix Multivitamin Fifty Plus?
The vitamin E in the nutraMetrix Isotonix Multivitamin Fifty Plus is the natural, high activity d, 1-alpha-tocopherol. It has been converted to the acetate form to aid water solubility. This form of vitamin E, the natural form, is superior in terms of absorption and retention in the body. The natural form of alpha-tocopherol is known as d-alpha tocopherol, whereas the synthetic form is called dl-alpha tocopherol. The synthetic dl- form is the most common form found in dietary supplements, although many manufacturers, including Market America, have switched over to the more powerful (and expensive) natural d- form.
7. Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases. The US RDA's Human Nutrition Center on Aging claims vitamin B12 is the most important nutrient negatively affected by aging. Since vitamin B12 plays a critical role in promoting normal energy production and nervous system function, aging individuals need to make sure they are getting enough vitamin B12 on a daily basis.*
8. Why doesn’t nutraMetrix Isotonix Multivitamin Fifty Plus contain copper?
nutraMetrix Isotonix Multivitamin Fifty Plus was formulated to exclude copper to support the aging brain’s neurologic retention. Studies show a multivitamin formulated with additional zinc in the absence of copper is a formula that best supports the metabolic and neurologic needs of an aging brain.*
9. Who should take nutraMetrix Isotonix Multivitamin Fifty Plus?
Everyone over the age of 50 would find it beneficial to enhance their diet with nutraMetrix Isotonix Multivitamin Fifty Plus. Even when eating a balanced diet, it is difficult to consume the optimal amounts of vitamins and minerals each day. Numerous studies have been conducted on the importance of vitamins and minerals. One should supplement with a multivitamin to assure that their daily nutrient intake is balanced and powerful enough to ensure sufficient intake, allowing for the best health possible.*
10. What is the serving size for nutraMetrix Isotonix Multivitamin Fifty Plus?
Adults ages 50 and up should take two (2) level capfuls mixed with four ounces (4 oz.) of water daily (once in the morning and once in the afternoon) or as directed by your healthcare provider.
11. Can I take nutraMetrix Isotonix Multivitamin Fifty Plus with my prescriptions medications?
If you are currently using prescription drugs, have an ongoing medical condition, or if you are pregnant or breastfeeding, consult your healthcare provider before using this product.
Science
- Rasmussen HM1, Johnson EJ. Nutrients for the aging eye. Clin Interv Aging. 8:741-8, 2013.
- Etten, E., et al. 1,25-Dihydroxycholecalciferol: Endocrinology Meets the Immune System. Proceedings of the Nutrition Society. 61: 375-380, 2002.
- Lenton, Kevin J., et al. Vitamin C Augments Lymphocyte Glutathione in Subjects with Ascorbate Deficiency. American Journal of Clinical Nutrition. 77: 189 – 195, 2003.
- Rink, L. and Kirchner, H. Zinc-Altered Immune Function and Cytokine Production. Journal of Nutrition. 130: 1407S-1411S, 2000.
- Villamor, E. and Fawzi, W. Effects of Vitamin A Supplementation on Immune Response and Correlation with Clinical Outcomes. Clinical Microbiology Reviews. 18: 446-464, 2005.
- Haase H, Mocchegiani E, Rink L. Correlation between zinc status and immune function in the elderly. Biogerontology. 7(5-6):421-8., 2006. Review.
- Haase H, Rink L. The immune system and the impact of zinc during aging. Immun Ageing. 12;6:9, 2009.
- Deluca H et al. Vitamin D: its role and uses in immunology. FASEB Journal. 15(14):2579-2585, 2001.
- Hayes C et al. The immunological functions of the vitamin D endocrine system. Cellular and Molecular Biology. 49(2):277-300, 2003.
- Hall, S. and Greendale, G. The Relation of Dietary Vitamin C Intake to Bone Mineral Density: Results from the PEPI Study. Calcified Tissue International. 63: 183-189, 1998.
- Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. Washington, D.C.: National Academy Press; 2000.
- Henning S et al. Glutathione blood levels and other oxidant defense indexes in men fed diets low in vitamin C. Journal of Nutrition. 121:169-175, 1991.
- Johnston C et al. Vitamin C elevates red blood cell glutathione in healthy adults. American Journal of Clinical Nutrition. 58(1):103-105, 1993.
- Lenton K et al. Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency. American Journal of Clinical Nutrition. 77(1):189-195, 2003.
- Frei B et al. Ascorbate is an outstanding antioxidant in human blood plasma. Proceedings of the National Academy of Sciences USA. 86(16):6377-6381, 1989.
- Kirsch M et al. Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. Evidence that ascorbate acts by re-reducing substrate radicals produced by peroxynitrite. J Biol Chem. 275(22):16702-16708, 2000.
- Burton G et al. Vitamin E: Antioxidant activity, biokinetics, and bioavailability. Annual Review Nutrition. 10:357-382, 1992.
- Slyshenkov V et al. Pantothenic acid and pantothenol increase biosynthesis of glutathione by boosting cell energetics. FEBS Lett. 569(1-3):169-172, 2004.
*These statements have not been evaluated by the Food and Drug Administration.
This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Customer Reviews
Displaying reviews 1 - 5 of 31
on
- Shop Consultant
50 plus multi vitamins
Perfect combination for elderly people I am 79 and I love taking them as my main multivitamin every day however they been on back order too long. Don’t know what to think.
Response from Customer Service:
June 25, 2025
Thank you so much for sharing your feedback and for making Isotonix® Multivitamin Fifty Plus a part of your daily routine. We’re delighted to hear that you love the product and find it a great fit for your needs. We sincerely apologize for the inconvenience caused by the backorder and understand how frustrating this can be. Please know that we’re working hard to get it back in stock as soon as possible. Your patience and loyalty mean a lot to us—thank you for being a valued member of our community!
on
- Shop Consultant
Over 50 Feeling Great
I have to admit that I am over 50 but I feel younger! As I am approaching 60, I felt like I needed to ensure that I was getting the vitamins/minerals someone my age needed and the Isotonix Multivitamin 50 Plus does just that! I have actually felt the difference since I started taking this product!
Response from Customer Service:
November 15, 2024
Thank you for your fantastic review of Isotonix® Multivitamin Fifty Plus! We're thrilled to hear that you're feeling younger and that the multivitamin is meeting your needs. It’s wonderful to know that you’ve noticed a change since you started taking our product. Your commitment to maintaining your well-being is inspiring. Thank you for choosing Isotonix® and sharing your positive experience with us!
on
- Shop Consultant
Love Love this product!
I'm 64 years old and hated taking pill vitamins. Then I found Isotonix multivitamins Fifty Plus after loving the premeasured packets! I loved them, but this is more targeted to my specific needs! My health is great, and my energy is even better!
Response from Customer Service:
October 14, 2024
Thank you for sharing your experience with Isotonix® Multivitamin Fifty Plus! We're delighted to hear that you love the convenience and targeted support it provides. It's fantastic to know that it's helping you feel energized and meeting your specific needs. Your satisfaction and enthusiasm mean a lot to us. If you have any questions or need assistance, please feel free to reach out. Thank you for choosing us!
on
- Shop Consultant
Best kept secret
I am a 60 year old female and I don't eat enough mix of food for optimal health, but with this product it has more vitamins and minerals which they knew we would need, This is one vitamin I don't miss taking daily.
Response from Customer Service:
August 31, 2024
Thank you for sharing your experience with Isotonix® Multivitamin Fifty Plus! We're thrilled to hear that it has become an essential part of your daily routine and helps you achieve optimal health. It's wonderful to know that it provides the vitamins and minerals you need. Your feedback is greatly appreciated!
on
Excellent.
Taking this powder form of supplement definitely is more beneficial for me. I feel a positive difference with taking this product.
Response from Customer Service:
March 4, 2024
Dear Valued Customer,
Thank you for your positive feedback on our nutraMetrix Isotonix® Multivitamin Fifty Plus! We're glad to hear that you're experiencing positive benefits from taking the supplement. If you have any questions or need further assistance, feel free to reach out.
Thank you again,
The Product Information Team